教員紹介

研究活動・研究テーマ

【専門分野】
薬理学
【研究テーマ】
1.疼痛（神経障害性疼痛・ミクログリア・性差）
2.掻痒

著書・論文等

【論文】
1.Tas2R signaling enhances mouse neutrophil migration via a ROCK-dependent pathway.
Front Immunol. 2022 Aug 18;13:973880.

2.Chemogenetic activation of central gastrin-releasing peptide-expressing neurons elicits itch-related scratching behavior in male and female mice. Pharmacol Res Perspect. 2021 May;9(3):e00790.

3.Chemogenetic Activation of CX3CR1-Expressing Spinal Microglia Using Gq-DREADD Elicits Mechanical Allodynia in Male Mice. Cells. 2021 Apr 12;10(4):874.

4.Chemogenetic Regulation of CX3CR1-Expressing Microglia Using Gi-DREADD Exerts Sex-Dependent Anti-Allodynic Effects in Mouse Models of Neuropathic Pain.
Front Pharmacol. 2020 Jun 19;11:925.

5.GRP receptor and AMPA receptor cooperatively regulate itch-responsive neurons in the spinal dorsal horn. Neuropharmacology. 2020 Jun 15;170:108025.

6.Inflammatory Macrophages in the Sciatic Nerves Facilitate Neuropathic Pain Associated with
Type 2 Diabetes Mellitus. J Pharmacol Exp Ther. 2019 Mar;368(3):535-544.

7.Chemokine CXCL1 is responsible for cocaine-induced reward in mice.
Neuropsychopharmacol Rep. 2018 Sep;38(3):145-148.

8.Inhibition of peripheral macrophages by nicotinic acetylcholine receptor agonists suppresses spinal microglial activation and neuropathic pain in mice with peripheral nerve injury.
J Neuroinflammation. 2018 Mar 27;15(1):96.

9.Upregulation of CCL7 and CCL2 in reward system mediated through dopamine D1 receptor signaling underlies methamphetamine-induced place preference in mice.
Neurosci Lett. 2018 Feb 5;665:33-37.

10.Peripheral alpha4beta2 nicotinic acetylcholine receptor signalling attenuates tactile allodynia and thermal hyperalgesia after nerve injury in mice.
Acta Physiol (Oxf). 2015 Feb;213(2):462-71.

主な所属学会

日本薬理学会